Chrons Disease basics

Some Basic Chrons Disease facts: What it is and some of the main Chrons Disease Symptoms

Often when you are trying to research a medical condition like Crohn's Disease, you get bombarded with long words and medical terminology. In this article I will try and explain what chrons disease is in really basic terms. Hope it helps

So What is Chrons Disease?
Basicall Chrons disease is a medical condition that causes inflammation of the gastrointestinal tract which is sometimes known as the gut.

So what is the gut then?
When medical people talk of the gut, they mean your oesophagus (where your food first goes down after swallowing it!), your stomach, and your small and large intestines.

People cant be affected by Chrons disease in any part of the gut, but it seems to occur more often in the lower part of your small intestine, this part of your intestine is known as the ileum.

How do I know if I have Chrons Disease and what are the basic Chrons Disease symptoms?
The most common symptoms of chrons disease include, pain, which is often in your lower abdomen or stomach, ulcers and diarrhoea.

What can be done to help with the Chrons Disease Symptoms?
If you are diagnosed with Crohn's disease, you may be given medication that you will take daily that can help relieve your symptoms. Sometimes the medication will not work and you may have to have surgery to remove part of your gut, that has been affected with chrons disease.

So how common is Chrons Disease?
Chrons Disease is probably more common than you may have thought, about 1 person in 1,500 people have Chrons disease.

Chrons Disease can start at any age, but most often first shows up between the ages of 15 and 40. The disease also seems to affect slightly more women than men.

What is the Prognosis of Chrons Disease?
If you have Chrons disease, what is your outlook? This can be difficult to answer as it will depend largely what part of your gut has the disease and how bad a case of chrons disease you have. But if we work on an average case of Chrons, most people will experience some symptoms from time to time - this is called a flare up.

Most people who have chrons disease (about 80 %) will eventually have surgery at some time, probably to remove the diseased part of your gut.

Only in very rare cases where there is a complication, will Chrons Disease be life-threatening.

Chrons Disease Prognosis

So you have been diagnosed with chrons disease, after the initial shock, many people want to know what the outlook is, or the prognosis of chrons disease?

Again as with many questions involving Chrons Disease, there is no straight answer and the outlook tends to be quite variable. It all depends on which part or parts of your gut have been affected with chrons, how frequent and how severe your flare-ups are.

The Stats on a Chrons Disease Prognosis
Around Eight out of every Ten people who have Chrons disease will eventually require some sort of surgery at some stage in their life. About 50% of people with Chrons disease surgery is required within the first 10 years from the emergence of the disease.

Why do most people with chrons disease need surgery?
Is seems that the most common reason is to relieve an abnormal contraction that has formed in your gut.

Some people with chrons disease require more than one operation in their lifetime and if your chrons disease developed as a young adult, the average is to have between 2 and 4 operations in your lifetime. The good news in all this glum is that you CAN expect to have a good quality of life for most of the time, and it is important not to forget that!

Stats on Chrons Disease Flare-ups
Around 15% of people who have crohns disease have frequent and / or severe flare-ups. Again this is not a fixed number as a few people with Chrons disease have just one or two flare-ups in their whole life and spend most of their lives with no symptoms of the disease. The most likely prognosis is that you fall somewhere in between and have flare-ups from now and again and can have long periods of time without any symptoms of Chrons Disease.

It is important to keep in mind that a severe flare-up is and can be life threatening and there are some people who die as a result of a serious complication like a perforated gut, so you should always seek professional medical advice if you suspect that you are having a Chrons disease flare up .

Three Quick Chrons Disease Facts

As I don't have a lot of time today I am just going to pass on thre interesting facts on Chrons Disease that I have managed to dig up in my research:

First of the correct spelling is actually Crohn's Disease. The Cisease is named after Dr Crohn, who in the 1930's identified the disease.

You can get crohns disease at any age and it is still not fully understood why you get it although they do know that chrons disease is hereditary.

For every one thousand people living in the UK, about one person has Crohns disease

What are the Complications associated with Chrons Disease?

Most complications associated with Chrons Disease end up with abdominal pain to different degrees. The obstruction of the bowl, narrowing and perforation, or ulcers, scarring, abscesses and inflammation, can all result in abdominal pain and sometimes nausea and vomiting.

Because of this, it sometimes means that the intestines cannot absorb enough nutrition from the food that you are eating and this can lead to deficiencies, diarrhea can lead to dehydration and rectal bleeding to anemia.

The narrowing of your intestines with Chrons Disease can be because of swelling and scar tissue which result in blockages. Ulcers can eat into the walls of the intestines and can affect the surrounding tissue of organs like the bladder, vagina or the abdominal cavity. This burrowing causes a tube-like tunnel which is called a fistula, if the fistula becomes infected it causes abscess and recurrent infections.

Sometimes Chrons Disease is also associated with inflammation of the joints, arthritis, skin problems and inflammation of the eyes or mouth.

What causes Chrons disease?

Cause of Chrons Disease
Even though there is loads of research that is ongoing, the exact cause of Chrons disease is still unknown.

There are some researchers that suspect that infection by certain bacteria, probably strains of mycobacterium, may be the cause of Chrons disease. Unfortunately up to now, there has been no hard evidence that the disease is caused by infection.

The good news is that Chrons disease is not contagious, it cannot be passed on by blood or in the air. Even though your diet may affect the symptoms of your Chrons disease it is probably not anything to do with diet that caused you to get the disease.

ChronsDisease and the Immune System
In Inflammatory Bowel Disease (IBD) the activation of the immune system in the intestines seems to have some significance. Your immune system is made up of immune cells and the proteins that these immune cells make. The function of these cells and their proteins is to protect the body against harmful viruses, bacteria, fungi and other foreign bodies. When they are activated it causes inflammation inside the tissues where this activation occurs. This is natural and this is important as part of the defense used by your immune system.

In people who have IBD, the immune system is seems to be activated even though there is no known invader and it is this continued activation which causes the chronic inflammation and ulceration. It seems that this condition and your chances of getting Chrons disease is passed on genetically from your parents. So if your parents have IBD, you are are more likely to develop Crohn's Disease.

Recent research has discovered that a gene called NOD2 has something to do with Chrons disease and it has been found that it is important in determining how the body reacts to some bacterias. The research also showed that people who have mutations of NOD2 are more likely to developing Chrons disease.

New help to distinguish between Chrons Disease and Ulcerative Colitis in Children

Anti-glycan antibodies can help distinguish between Chrons disease and ulcerative colitis in children. This news was released at the United European Gastroenterology Week (UEGW) where researchers looked at the diagnostic relevance of serological anti-glycan antibodies in 110 young people less than 18 years old who had inflammatory bowel disease (IBD) and 630 people older than 18 years.

There has always been a problem in diagnosing people who either have chrons disease or ulcerative colitis as they are very similar and have many overlapping features, but the correct diagnosis is important for the correct form of treatment. Traditionally paediatric patients often have to endure invasive examination of combined upper endoscopy, colonoscopy, and terminal ileoscopy with biopsies and atthe end of this the exact disease (crohn's disease or ulcerative colitis) in up to 30% of patients is still unknown and they are defined as "indeterminate colitis" or unclassified inflammatory bowel disease.

In adult patients, anti-glycan antibodies IBDX has been found to help distinguish between Chrons disease and ulcerative colitis, so it is highly likely that IBDX markers may also help in the diagnosis of paediatric IBD patients. The hope is that this will reduce the use of invasive examination in young children.

During the tests, the diagnosis of IBD for each person was based upon standard endoscopic, histologic, and radiographic criteria and serological analysis of antibodies against mannan epitope of Saccharomyces cerevisiae (gASCA), laminaribioside (ALCA), chitobioside (ACCA), and mannobioside (AMCA) were performed using IBDX ELISA panel.


The Results
In the results of the tests, children with IBD, who tested positive for at least one of the markers could be identified as Chrons disease patients with a sensitivity of 65% and specificity of 84%; the positive and negative predictive values were 91% and 50%, respectively. Children who tested positive for 2 or more markers could be identified as Chrons disease with higher specificity (94%) but lower sensitivity (22%).


There were also no significant differences in the results between children and adults with IBD.

The Conclusion
So in conclusion these tests show for the first time that similar to adults, anti-glycan antibodies can distinguish between chrons disease and ulcerative colitis in children with IBD.

Children with Chrons disease often picky eaters

In a new study that was looking into food and the eating patterns in children with inflammatory bowel disease (IBD) which is a condition that includes Chrons disease and ulcerative colitis, it was found that children with IBD and crohn's disease are more likely than other children to show signs of picky eating.

All the children in the study had either Chrons disease or ulcerative colitis and "Picky" eating was defined as not eating during meal time, trying to negotiate with their parents what they will or won't eat and completely refusing to eat certain foods.


Dr. Laura Mackner the author of the study from the Columbus Children's Research Institute and Ohio State University told said the results found that children with chrons disease or ulcerative colitis have a significantly more eating behavioral problems and these also occur more often than in healthy children. She also said that children with IBD often feel pains in their abdomen, which may make them not want to eat food. "If your stomach's hurting, you may not feel like eating," she said.

Chrons Disease and a Childs Diet
Often children who have a form of IBD, weather it be Chrons disease or ulcerative colitis are often smaller than other children their own age this often makes their parents try to force them to eat more, often creating tension and a power struggle over eating. Dr. Laura Mackner said that as a parent who has a child who's eating habits start to interfere with their health you should consider taking your child to a psychologist who has experience in eating behaviors.

Nutrition education and behavior management has helped children overcome eating problems in other diseases, and similar programs might also work for children with chrons disease or ulcerative colitis.

The study looked into the eating behaviors of 82 children all between the ages of 11 and 17. 50 of the children had inflammatory bowel disease (IBD) and the rest were healthy.

They also found that girls with chrons disease or ulcerative colitis and who were unhappy with their bodies showed a higher risk of eating problems. How much they weighed was not important. But with boys who had crohn's disease or ulcerative colitis weight was important, and those who weighed less than their peers were more likely to develop eating problems than normal weight boys with IBD.

These results of this study were presented during the recent meeting of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition in Montreal.

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